Dynamic dialysis is ideal for the purification of viscous fluids and hydrogels (hyaluronic acid – HA) that cannot be filtered. Where traditional filtration methods may fail, dynamic dialysis uses flow dynamics to increase both the rate and efficiency of dialysis.
The Dynamic Dialysis Recirculation Tank makes dialysis of larger sample volumes ranging from 100 ml to 2 liters faster and more efficient. By enabling a continuous buffer flow, the system maintains a higher concentration gradient and faster rate of dialysis compared to traditional static dialysis with manual buffer changes.
Allows for a continuous buffer flow (50-200ml/min) from a remote dialysis feed reservoir (up to 1000 L); higher sample purity
Shorter run time, no manual buffer changes, smaller buffer volume required
The tall, cylindrical tank enables the efficient removal of solutes by keeping the buffer close to the membrane surface; small footprint
|3 Volume Sizes||5 liter||7 liter||10 liter|
|Total height||68 cm||86 cm||126 cm|
|Base width||30.5 cm||30.5 cm||30.5 cm|
|Internal diameter||10.5 cm||10.5 cm||10.5 cm|
|2 Modes of operation|
|Recirculation mode||Buffer flow returned to remote source|
|Single-pass mode||Buffer flow directly to discharge/drain|
|1.5 in. x ¼ in. Hose Barb Adaptor||Polypropylene||2|
|1.5 in. x ⅜ in. Hose Barb Adapto||Polypropylene||1|
|6 inch gasket||Silicone Pt-cured||1|
|1.5 inch gasket||Silicone Pt-cured||2|
|6 inch clamp||Nylon||1|
|1.6 inch clamp||Nylon||2|
|Silicone Tubing, Pharmapure 10’ x ¼ in. ID||Silicone||1|
|Silicone Tubing, Platinum-cured, 10’ x ⅜ in. ID||Silicone||1|
With the ability to support 6 dialysis process tanks in series, the Dynamic Dialysis Cart is a compact rolling wet workstation, ready for GMP manufacturing.
Range of of tank sizes for scalability and faster contaminant clearance
Run multiple systems in series on cart or multiple process scale systems; easy buffer loading and draining
Up to 6 tanks in series; 12 liter batch sizes; biosectors for low-cost scalability
Collapsible shelves and tubing hooks, drain manifold, secondary containment; spill-free sample preparation; compact storage
ISO 9001:2015 certified; Meets USP Class VI biosafety requirements; Raw materials meet 21 CFR 177.1520 requirements; Phthalates, BPA, DHEP, and BSE/TSE free
Worldwide application support
The KrosFlo® KR1 Pump controls the speed of the pump heads to provide flow rates from 0.06 to 2300 mL/min.
|2 Models / Speeds||Maximum number of pump heads|
|1 - 100 rpm||2|
|6 - 600 rpm||
The Spectra/Por® Cart is a rolling work station that can support up to 6 dialysis recirculation tanks in series.
|Up to 6 tanks in series, 12 L batch sizes||Easy buffer management|
|Wet workstation||Spill-free sample preparation|
|BSE/TSE free polypropylene construction||Ready for GMP manufacturing|
|Collabsible shelves and tubin hooks||Compact storage|
|Drain manifold||Convenientbuffer loading and draining|
|Secondary containment||No lab spills|